BDBM50149219 3-(3'-Cyanomethyl-biphenyl-4-yloxy)-N-hydroxy-propionamide::CHEMBL116756

SMILES ONC(=O)CCOc1ccc(cc1)-c1cccc(CC#N)c1

InChI Key InChIKey=WCEYHKKUIBHLOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149219   

TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50149219(3-(3'-Cyanomethyl-biphenyl-4-yloxy)-N-hydroxy-prop...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MMP3 (unknown origin) using Ac-Pro-Leu-Gly-[2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50149219(3-(3'-Cyanomethyl-biphenyl-4-yloxy)-N-hydroxy-prop...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed