BDBM50150522 CHEMBL3771315

SMILES COc1cc(CNC(=O)Nc2ccc(cc2)C(C)(C)C)ccc1B(O)O

InChI Key InChIKey=ANLHFFUCNTWGQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150522   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150522BDBM50150522(CHEMBL3771315)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150522BDBM50150522(CHEMBL3771315)
Affinity DataIC50: 8.11E+3nMAssay Description:Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed