BDBM50150555 1-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl]-phenoxy}-propyl)-4-methyl-piperazine::CHEMBL365671

SMILES CN1CCN(CCCOc2ccc(cc2)-c2nc(no2)-c2ccc(Cl)cc2)CC1

InChI Key InChIKey=XJRSTLZTWSTPSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150555   

TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150555(1-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150555(1-(3-{4-[3-(4-Chloro-phenyl)-[1,2,4]oxadiazol-5-yl...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of interleukin-8 induced elastase release from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed