BDBM50151366 (2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-piperazin-1-yl)-2,5,9,9b-tetraaza-cyclopenta[a]naphthalen-4-yl]-amine::BMS-279700::CHEMBL189338

SMILES: C[C@H]1CN(CCN1)c1ccc2nc(Nc3c(C)cccc3Cl)c3cncn3c2n1

InChI Key: InChIKey=PUNYTBZWCMNSRO-UHFFFAOYSA-N

Data: 19 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50151366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MO15-related protein kinase Pfmrk (malaria parasite P. falciparum)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase HCK (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>23	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.70	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fgr (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.80	n/a	n/a	n/a	n/a	n/a	n/a
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O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11/12/13/14 (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>380	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1/2/3 (Human)	BDBM50151366 ((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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