BDBM50151473 (1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-(naphthalen-2-ylmethoxy)-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid::CHEMBL185210

SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1ccc3ccccc3c1)[C@]2(F)C(O)=O)C(O)=O

InChI Key InChIKey=BBDMJGONEUTSEP-HIGHGGLBSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151473   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151473((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-(naphthalen-2-...)
Affinity DataKi:  2.53nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]-MGS0008More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151473((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-(naphthalen-2-...)
Affinity DataKi:  5.43nMAssay Description:Binding affinity towards metabotropic glutamate receptor 3 of rat expressed in CHO cells was determined by using [3H]-MGS0008More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151473((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-(naphthalen-2-...)
Affinity DataIC50:  22.7nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 2 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed