BDBM50153982 2-(4-Ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine::CHEMBL364804

SMILES CCOc1ccc(cc1)-c1nn2ncccc2c1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=NXMZBNYLCVTRGB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153982   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153982(2-(4-Ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)
Affinity DataIC50: >8.42E+4nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50153982(2-(4-Ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human COX-2 expressed in human COS cells using arachidonic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50153982(2-(4-Ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-p...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed