BDBM50158830 CHEMBL3785583

SMILES CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1cnn(c1)C(C)(C)C

InChI Key InChIKey=KRXWJZIHQRIGSJ-UHFFFAOYSA-N

Data  10 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50158830   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5A (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataEC50:  180nMAssay Description:Inhibition of KDM5A in human PC9 cells assessed as reduction in demethylation of H3K4me3 after 120 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataEC50:  180nMAssay Description:Inhibition of KDM5B in human PC9 cells assessed as reduction in demethylation of H3K4me3 after 120 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  66nMAssay Description:Inhibition of KDM5C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  66nMAssay Description:Inhibition of KDM5C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  15nMAssay Description:Inhibition of KDM5A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  15nMAssay Description:Inhibition of KDM5A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of KDM4C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of KDM4C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed