BDBM50158940 2-Pyridin-3-yl-pyrimidine::CHEMBL178878::US8609708, 41::cid_13349629

SMILES c1cnc(nc1)-c1cccnc1

InChI Key InChIKey=DYEAIDZAOQKZJM-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50158940   

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158940(US8609708, 41 | CHEMBL178878 | cid_13349629 | 2-Py...)
Affinity DataKi:  1.80E+3nMAssay Description:Effect on coumarin 7-hydroxylation by human Cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158940(US8609708, 41 | CHEMBL178878 | cid_13349629 | 2-Py...)
Affinity DataIC50: 1.09E+4nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50158940(US8609708, 41 | CHEMBL178878 | cid_13349629 | 2-Py...)
Affinity DataIC50: 1.00E+5nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetCytochrome P450 3A4(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158940(US8609708, 41 | CHEMBL178878 | cid_13349629 | 2-Py...)
Affinity DataIC50: 4.00E+5nMAssay Description:To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of othe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent