BDBM50161518 1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one::1-Oxazolo[4,5-b]pyridin-2-yl-6-phenyl-hexan-1-one::CHEMBL175854
SMILES O=C(CCCCCc1ccccc1)c1nc2ncccc2o1
InChI Key InChIKey=VPZHQLPAKFVGKX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50161518
Affinity DataKi: 0.0940nMAssay Description:Binding affinity for human fatty acid amide hydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0940nMAssay Description:Inhibition of human recombinant FAAHMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding affinity for rat fatty acid amide hydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibitor affinity of the compound towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or ...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of DAGLalpha in mouse brain proteome pre-incubated for 30 mins followed by ABP MB064 probe addition for 15 mins by ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of DAGLalpha in mouse brain proteome pre-incubated for 30 mins followed by ABP MB064 probe addition for 15 mins by ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human DAGLalpha expressed in HEK293T cell membrane fractions using PNP butyrate as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of FAAH in rat brain microsomes using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate after 60 mins by fluorescence-based reversed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain microsomes assessed as N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide conversion to 4-pyren-1-ylbutanoic ac...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome FAAH assessed as reduction in 4-pyren-1-ylbutanoic acid release after 60 mins by reverse phase HPLC-...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of FAAH from rat brain microsomes by RP-HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against Fatty-acid amide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against Triacylglycerol hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human DAGLalpha expressed in HEK293T cell membrane fractions using PNP butyrate as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration of triacylgylcerol hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair