BDBM50162888 CHEMBL426604::[2-(4-Fluoro-phenyl)-ethyl]-(1H-imidazol-4-ylmethyl)-(4-phenoxy-benzyl)-amine

SMILES Fc1ccc(CCN(Cc2cnc[nH]2)Cc2ccc(Oc3ccccc3)cc2)cc1

InChI Key InChIKey=GSHROJORMPAUBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162888   

LigandPNGBDBM50162888([2-(4-Fluoro-phenyl)-ethyl]-(1H-imidazol-4-ylmethy...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50162888([2-(4-Fluoro-phenyl)-ethyl]-(1H-imidazol-4-ylmethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed