BDBM50164693 CHEMBL194721::N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(2-chloro-phenyl)-5-trifluoromethyl-pyrimidine-2,4-diamine

SMILES FC(F)(F)c1cnc(Nc2ccc3nc[nH]c3c2)nc1Nc1ccccc1Cl

InChI Key InChIKey=UEYQVGAFBVFHAU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50164693   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50164693(CHEMBL194721 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50:  1nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164693(CHEMBL194721 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50:  29nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164693(CHEMBL194721 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against Extracellular signal-regulated kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164693(CHEMBL194721 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50:  29nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50164693(CHEMBL194721 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50164693(CHEMBL194721 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50:  2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164693(CHEMBL194721 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed