BDBM50166435 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE::5-(4-Methoxy-biphenyl-3-yl)-1,1-dioxo-1lambda*6*-[1,2,5]thiadiazolidin-3-one::5-(4-Methoxy[1,1'-biphenyl]-3-yl)-1,2,5-thiadiazolidin-3-one 1,1-Dioxide (2a)::CHEMBL193233

SMILES COc1ccc(cc1N1CC(=O)NS1(=O)=O)-c1ccccc1

InChI Key InChIKey=IGXKSKWHHHYBFM-UHFFFAOYSA-N

Data  1 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50166435   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-322](Homo sapiens (Human))
University Of Missouri

LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataKi:  2.40E+3nM IC50:  4.80E+3nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50166435(5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-...)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibitory concentration against Protein tyrosine phosphatase 1BMore data for this Ligand-Target Pair