BDBM50167925 CHEMBL3798047
SMILES COc1cc(ccc1-c1cc(cc2[nH]ncc12)C(F)(F)F)C(=O)NCCO
InChI Key InChIKey=MQBAPASGXUTVKD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50167925
Affinity DataIC50: 13nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Inhibition of MetAP2 in HUVEC assessed as accumulation of N-Met-14-3-3gamma after 24 hrs by Western blot methodMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of human CYP1A2 expressed in Escherichia coli DH5-alphaMore data for this Ligand-Target Pair