BDBM50172062 CHEMBL3806108
SMILES CN(C)c1ccc(cc1)C1CC(=NN1c1ccccc1)c1ccc2OCCOc2c1
InChI Key InChIKey=XYBLZFUVTDZOBZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50172062
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged EGFR (unknown origin) cytoplasmic domain (645 to 1186 residues) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr befor...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Mus musculus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...More data for this Ligand-Target Pair