BDBM50173334 CHEMBL3809935

SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1OC1CCN(CC1)C(=O)c1ccncc1

InChI Key InChIKey=XFHUWXYRCAAZHK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50173334   

TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50173334(CHEMBL3809935)
Affinity DataIC50: 99nMAssay Description:Inhibition of His-tagged human recombinant cKIT expressed in baculovirus using Tyr 06 peptide as substrate after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50173334(CHEMBL3809935)
Affinity DataIC50: 120nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human PDGFRbeta (amino acids 557-end) expressed in baculovirus infected insect Sf9 cells using Poly(4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50173334(CHEMBL3809935)
Affinity DataIC50: 126nMAssay Description:Inhibition of GST-tagged human DDR1 expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50173334(CHEMBL3809935)
Affinity DataIC50: 133nMAssay Description:Inhibition of His-tagged recombinant human CSF1R expressed in baculovirus expression system after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed