BDBM50175780 CHEMBL200435::N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-hydroxy-N-methylurea

SMILES CN(CCOc1ccc(cc1)-c1ccc(cc1)C#N)C(=O)NO

InChI Key InChIKey=GVMUNGGWXRKCEU-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175780   

TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50175780(CHEMBL200435 | N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50175780(CHEMBL200435 | N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)...)
Affinity DataIC50:  1.20E+6nMAssay Description:Inhibitory activity against MMP8More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50175780(CHEMBL200435 | N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibitory activity against MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed