BDBM50175921 1-cyclobutyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL200877

SMILES O=C1NCN(C2CCC2)C11CCN(CC1)[C@H]1CCCC[C@H]1c1ccccc1

InChI Key InChIKey=SYGCNNXMTSJKQR-SFTDATJTSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175921   

TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175921(1-cyclobutyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT2 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175921(1-cyclobutyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8...)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed