BDBM50177274 4'-trifluoromethyl-biphenyl-4-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-amide::CHEMBL202854

SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)c3ccc(cc3)-c3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key InChIKey=FCYYWOZROBLFFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177274   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177274(4'-trifluoromethyl-biphenyl-4-carboxylic acid {2-[...)
Affinity DataIC50:  474nMAssay Description:Displacement of [3H]myo-inositol from human MCH1 receptor expressed in CHO cell by IP3 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177274(4'-trifluoromethyl-biphenyl-4-carboxylic acid {2-[...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in CHO cell by WC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177274(4'-trifluoromethyl-biphenyl-4-carboxylic acid {2-[...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human MCH1 receptor by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed