BDBM501787 4-(6-{decahydropyrrolo[3,4- d]azepin-6-yl}-4-methyl-3-(4- methylphenyl)-5-oxo-4,5- dihydropyrazin-2-yl)benzonitrile::US11028066, Example 25

SMILES Cc1ccc(cc1)-c1c(nc(N2CCC3CNCC3CC2)c(=O)n1C)-c1ccc(cc1)C#N

InChI Key InChIKey=FUKABXYCAMJWMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501787   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM501787(4-(6-{decahydropyrrolo[3,4- d]azepin-6-yl}-4-meth...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent