BDBM50178708 CHEMBL3814251

SMILES OC(=O)c1cc2ncc(Cl)cc2n1Cc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HFVXRVDWIOTTNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178708   

TargetC-C chemokine receptor type 9(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178708(CHEMBL3814251)
Affinity DataIC50:  113nMAssay Description:Antagonist activity at CCR9 (unknown origin) assessed as inhibition of TECK-stimulated calcium mobilization preincubated for 10 mins followed by agon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 9(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178708(CHEMBL3814251)
Affinity DataIC50:  590nMAssay Description:Inhibition of CCR9-mediated chemotaxis in human MOLT4 cells preincubated for 10 mins followed by TECK addition in presence of 0.1% BSA measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed