BDBM501800 4-[6-(4-amino-piperidin-1-yl)-3- (4-cyclopropyl-phenyl)-4-(2- hydroxy-ethyl)-5-oxo-4,5-dihydro- pyrazin-2-yl]-benzonitrile::US11028066, Example 38

SMILES NC1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(cc2)C2CC2)n(CCO)c1=O

InChI Key InChIKey=PUIOIFVTVNOUJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501800   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM501800(4-[6-(4-amino-piperidin-1-yl)-3- (4-cyclopropyl-p...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent