BDBM501800 4-[6-(4-amino-piperidin-1-yl)-3- (4-cyclopropyl-phenyl)-4-(2- hydroxy-ethyl)-5-oxo-4,5-dihydro- pyrazin-2-yl]-benzonitrile::US11028066, Example 38
SMILES NC1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(cc2)C2CC2)n(CCO)c1=O
InChI Key InChIKey=PUIOIFVTVNOUJL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501800
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair