BDBM50180349 2-(4-Methoxyphenyloxyethylamino)-6-(3-acetamidophenyl)-pyrazine::CHEMBL198400

SMILES COc1ccc(OCCNc2cncc(n2)-c2cccc(NC(C)=O)c2)cc1

InChI Key InChIKey=GRJCMBQOXBJUJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180349   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180349(2-(4-Methoxyphenyloxyethylamino)-6-(3-acetamidophe...)
Affinity DataIC50:  3.80E+4nMAssay Description:Growth inhibition in human melanoma cells WM266.4 expressing mutant B-RAF with SRBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180349(2-(4-Methoxyphenyloxyethylamino)-6-(3-acetamidophe...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibitory activity against human B-RAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed