BDBM501817 2-fluoro-4-{3-(4-methoxy- phenyl)-4-methyl-5-oxo-6-[((3S)- pyrrolidin-3-ylmethyl)-amino]- 4,5-dihydro-pyrazin-2-yl}- benzonitrile::US11028066, Example 55
SMILES COc1ccc(cc1)-c1c(nc(NC[C@H]2CCNC2)c(=O)n1C)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=HMNSDEAJDFBELC-HNNXBMFYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501817
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair