BDBM50181754 2-methyl-4-[[3-(trifluoromethyl)phenyl]ethynyl]thiazole::CHEMBL370142

SMILES Cc1nc(cs1)C#Cc1cccc(c1)C(F)(F)F

InChI Key InChIKey=FFBFCGDHUGTWJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181754   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50181754(2-methyl-4-[[3-(trifluoromethyl)phenyl]ethynyl]thi...)
Affinity DataIC50:  413nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed