BDBM50182568 1-(4-N-methylpyrrolephenyl)-2-pyrrolidin-1-yl-pentan-1-one::CHEMBL377510

SMILES CCCC(N1CCCC1)C(=O)c1ccc(cc1)-c1cccn1C

InChI Key InChIKey=ROXOOMBIDGERBZ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182568   

TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182568(1-(4-N-methylpyrrolephenyl)-2-pyrrolidin-1-yl-pent...)
Affinity DataKi:  3.85E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182568(1-(4-N-methylpyrrolephenyl)-2-pyrrolidin-1-yl-pent...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182568(1-(4-N-methylpyrrolephenyl)-2-pyrrolidin-1-yl-pent...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182568(1-(4-N-methylpyrrolephenyl)-2-pyrrolidin-1-yl-pent...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed