BDBM50182709 4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-1H-pyrazol-3-yl)-6-phenethylbenzene-1,3-diol::CHEMBL207757

SMILES CS(=O)(=O)c1ccc(CN2CCN(CC2)c2c[nH]nc2-c2cc(CCc3ccccc3)c(O)cc2O)cc1

InChI Key InChIKey=YBGGSTRJIWHNQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182709   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182709(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182709(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed