BDBM50183538 (R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(4-phenylbutan-2-ol)-piperidine oxalate::CHEMBL202860

SMILES O[C@H](CCc1ccccc1)CN1CCC(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1

InChI Key InChIKey=GLGCNDZGYPRTRL-GDLZYMKVSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50183538   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183538((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]DA uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183538((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]RTI-55 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183538((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]RTI-55 from SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183538((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)
Affinity DataKi:  19nMAssay Description:Inhibition of [3H]5HT uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183538((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)
Affinity DataKi:  79nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183538((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)
Affinity DataKi:  460nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed