BDBM50183807 3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)-N-phenylbenzamide::CHEMBL207775

SMILES CC(C)(c1cc(-c2cccc(c2)C(=O)Nc2ccccc2)c2ncccc2c1)S(C)(=O)=O

InChI Key InChIKey=APHANYYADPNRCL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50183807   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183807(3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human GST-PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183807(3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human GST-PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183807(3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human GST-PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183807(3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)...)
Affinity DataIC50: 97nMAssay Description:Inhibition of human GST-PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183807(3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)...)
Affinity DataIC50: 7.00E+3nMAssay Description:Ability to block TNFalpha release through inhibition of PDE4 in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed