BDBM501846 4-[5-(4-aminopiperidin-1-yl)-2-(3- fluoro-4-methoxyphenyl)-1- methyl-6-oxopyridin-3-yl]-2- fluorobenzonitrile::US11028066, Example 84

SMILES COc1ccc(cc1F)-c1c(cc(N2CCC(N)CC2)c(=O)n1C)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=CTWXOFMDXATANR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501846   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM501846(4-[5-(4-aminopiperidin-1-yl)-2-(3- fluoro-4-metho...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent