BDBM501849 4-[5-(4-aminopiperidin-1-yl)-1- ethyl-2-(4-methoxyphenyl)-6- oxopyridin-3-yl]-2- fluorobenzonitrile::US11028066, Example 87
SMILES CCn1c(-c2ccc(OC)cc2)c(cc(N2CCC(N)CC2)c1=O)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=KEFXVSWZJJSHAQ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501849
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair