BDBM50185852 7-hydroxy-3-oxo-9a-phenyl-2,3,9,9a-tetrahydro-1H-fluorene-4-carbonitrile::CHEMBL211739

SMILES Oc1ccc2C3=C(C#N)C(=O)CCC3(Cc2c1)c1ccccc1

InChI Key InChIKey=OFYSBBHTMBIDCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185852   

TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185852(7-hydroxy-3-oxo-9a-phenyl-2,3,9,9a-tetrahydro-1H-f...)
Affinity DataIC50:  880nMAssay Description:Binding affinity to ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185852(7-hydroxy-3-oxo-9a-phenyl-2,3,9,9a-tetrahydro-1H-f...)
Affinity DataIC50:  32nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed