BDBM50185937 3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydroxy-tetrahydro-furan-2-carboxylic acid methyl amide::CHEMBL377071

SMILES CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1N=[N+]=[N-])n1cnc2c(NCc3cccc(I)c3)ncnc12

InChI Key InChIKey=SVWWALKTOHAUAD-MHMFGPJMSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185937   

TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185937(3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydr...)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor H272D mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185937(3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydr...)
Affinity DataKi:  186nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor H272E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185937(3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydr...)
Affinity DataKi:  1.37E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor T94A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185937(3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydr...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor T94E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50185937(3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydr...)
Affinity DataKi:  2.26E+3nMAssay Description:Displacement of [125I]I-AB-MECA from wild type adenosine A3 receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed