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BDBM50187161 (S)-benzyl 1-(5-(4-((4-(trifluoromethyl)phenethyl)carbamoyl)benzyl)-1,2,4-oxadiazol-3-yl)-6-amino-1-oxohexan-2-ylcarbamate::CHEMBL414865

SMILES: NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NCCc2ccc(cc2)C(F)(F)F)n1

InChI Key: InChIKey=JMUOMUDAWFHUPQ-MHZLTWQESA-N

Data: 1 KI

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187161   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryptase beta-1/beta-2


(Homo sapiens (Human))
BDBM50187161
PNG
((S)-benzyl 1-(5-(4-((4-(trifluoromethyl)phenethyl)...)
Show SMILES NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NCCc2ccc(cc2)C(F)(F)F)n1
Show InChI InChI=1S/C33H34F3N5O5/c34-33(35,36)26-15-11-22(12-16-26)17-19-38-31(43)25-13-9-23(10-14-25)20-28-40-30(41-46-28)29(42)27(8-4-5-18-37)39-32(44)45-21-24-6-2-1-3-7-24/h1-3,6-7,9-16,27H,4-5,8,17-21,37H2,(H,38,43)(H,39,44)/t27-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
220n/an/an/an/an/an/an/an/a



Celera

Curated by ChEMBL


Assay Description
Inhibition of human beta tryptase


Bioorg Med Chem Lett 16: 4036-40 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.009
BindingDB Entry DOI: 10.7270/Q20864ZV
More data for this
Ligand-Target Pair