BDBM50187625 4-nitro-N-(1-(2-chlorophenyl)-3-phenyl-1H-pyrazol-5-yl)benzamide::CHEMBL207334

SMILES [O-][N+](=O)c1ccc(cc1)C(=O)Nc1cc(nn1-c1ccccc1Cl)-c1ccccc1

InChI Key InChIKey=LCJYQTQQCCWZMO-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187625   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187625(4-nitro-N-(1-(2-chlorophenyl)-3-phenyl-1H-pyrazol-...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50187625(4-nitro-N-(1-(2-chlorophenyl)-3-phenyl-1H-pyrazol-...)
Affinity DataEC50:  40nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed