BDBM50188266 7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole::CHEMBL213743

SMILES: CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1

InChI Key: InChIKey=OLLCPXMBOYVHAF-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50188266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1/2/3/4 (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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