BDBM50188851 CHEMBL211525::rac-4-(4-fluoro-phenyl)-8-(1-isopropyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one

SMILES CC(C)C1(CCCCC1)N1CCC2(CC1)C(CNC2=O)c1ccc(F)cc1

InChI Key InChIKey=WLNNXDHLQGPCSS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188851   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188851(CHEMBL211525 | rac-4-(4-fluoro-phenyl)-8-(1-isopro...)
Affinity DataEC50:  787nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed