BDBM50188867 4-phenyl-8-(3-phenyl-tetrahydro-pyran-3-yl)-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL446703

SMILES O=C1NCC(c2ccccc2)C11CCN(CC1)C1(CCCOC1)c1ccccc1

InChI Key InChIKey=HDXLFCMABRPUOD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188867   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188867(4-phenyl-8-(3-phenyl-tetrahydro-pyran-3-yl)-2,8-di...)
Affinity DataEC50:  1.42E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188867(4-phenyl-8-(3-phenyl-tetrahydro-pyran-3-yl)-2,8-di...)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed