BDBM50191290 3-((5-(2-chloro-4,5-dimethoxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid::3-(5-(2-chloro-4,5-dimethoxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylidene)amino)benzoic acid::CHEMBL378530

SMILES COc1cc(Cl)c(\C=C2/S\C(=N\c3cccc(c3)C(O)=O)N(C)C2=O)cc1OC

InChI Key InChIKey=OQLMEWQXUAYOHO-PAFNDRTPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191290   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50191290(3-((5-(2-chloro-4,5-dimethoxybenzylidene)-3-methyl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of integrin alphaVbeta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50191290(3-((5-(2-chloro-4,5-dimethoxybenzylidene)-3-methyl...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of [125I]echistatin binding to integrin alphaVbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50191290(3-((5-(2-chloro-4,5-dimethoxybenzylidene)-3-methyl...)
Affinity DataIC50:  0.0300nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 in human NCI-H1975 cells after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed