BDBM50191352 CHEMBL3936376

SMILES COc1ccc(cc1)-c1ccc2[nH]nc(C(O)=O)c2c1

InChI Key InChIKey=BBTNJRYVRKDPQM-UHFFFAOYSA-N

Data  1 Kd  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191352   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50191352(CHEMBL3936376)Copy SMILESCopy InChI

Affinity DataEC50:  3.39E+3nMAssay Description:Activation of recombinant human AMPK alpha1/beta1/gamma1 using Cy5-labelled SAMS as substrate assessed as protection from Thr172 residue dephosphoryl...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50191352(CHEMBL3936376)Copy SMILESCopy InChI

Affinity DataKd:  9.95E+3nMAssay Description:Binding affinity to recombinant human AMPK alpha1/beta1/gamma1 by SPR binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI