BDBM50193718 2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-but-2-enyl)-8H-pyrano[3,2-g]chromen-4-one::2-(2,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methylbut-2-enyl)pyrano[3,2-g]chromen-4(8H)-one::CHEMBL221907::cid_5319925::cudraflavone B

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(oc2cc3-[#8]C([#6])([#6])[#6]=[#6]-c3c(-[#8])c2c1=O)-c1ccc(-[#8])cc1-[#8]

InChI Key InChIKey=XIWCDUHPYMOFIL-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50193718   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50193718(2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50193718(2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-...)
Affinity DataIC50:  4.16E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50193718(2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant PTP1B catalytic domain (unknown origin) assessed as reduction in pNP formation using pNPP as substrate by absorbance based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Veterinary And Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM50193718(2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of ram seminal vesicle COX-1 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Mus musculus)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50193718(2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition at monoamine oxidase in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Veterinary And Pharmaceutical Sciences Brno

Curated by ChEMBL
LigandPNGBDBM50193718(2-(2,4-dihydroxy-phenyl)-5-hydroxy-8,8-dimethyl-3-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as PGE2 production from arachidonic acid after 20 mins enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed