BDBM50193874 7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazin-3-amine::7-(2,6-dimethylphenyl)-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-benzotriazin-3-amine::CHEMBL436137::US8481536, 322

SMILES: Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(OCCN4CCCC4)cc3)nnc2c1

InChI Key: InChIKey=YJSFAHMGDRBZGH-UHFFFAOYSA-N

Data: 3 KI  28 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 50193874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Fyn (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 4 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	25
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Platelet-derived growth factor receptor beta (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	965	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	678	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	555	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	659	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase beta-1 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Blk (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50193874 (CHEMBL436137 | US8481536, 322 | 7-(2,6-dimethylphe...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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