BDBM50196134 (R)-{4-[4-(3-methylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol::CHEMBL385722

SMILES C[C@@H]1CN(CCN1)c1ccc(Nc2c(CO)cnc3ccccc23)cc1

InChI Key InChIKey=MDMIXTNJRVJFQM-OAHLLOKOSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196134   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196134((R)-{4-[4-(3-methylpiperazin-1-yl)phenylamino]quin...)
Affinity DataKi:  205nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2C expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196134((R)-{4-[4-(3-methylpiperazin-1-yl)phenylamino]quin...)
Affinity DataKi:  205nMAssay Description:Binding affinity to human cloned Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196134((R)-{4-[4-(3-methylpiperazin-1-yl)phenylamino]quin...)
Affinity DataKi:  9.60E+3nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2A expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196134((R)-{4-[4-(3-methylpiperazin-1-yl)phenylamino]quin...)
Affinity DataKi:  1.76E+4nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2B expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed