BDBM50196926 CHEMBL438139::Rocaglamide::US10085988, Compound (-) Roc-A

SMILES: CN(C)C(=O)[C@@H]1[C@H]([C@]2([C@@]([C@@H]1O)(c3c(cc(cc3OC)OC)O2)O)c4ccc(cc4)OC)c5ccccc5

InChI Key: InChIKey=DAPAQENNNINUPW-UHFFFAOYSA-N

Data: 12 IC50  1 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50196926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (HCV)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	8.0	n/a
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Transcription factor p65 (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Transcription factor p65 (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	231	n/a	n/a	n/a	n/a	n/a	n/a
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Transcription factor p65 (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear factor NF-kappa-B p105 subunit (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription factor p65 (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription factor p65 (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription factor p65 (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear factor NF-kappa-B p105 subunit (Human)	BDBM50196926 (Rocaglamide | CHEMBL438139 | US10085988, Compound ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair