BDBM50198212 5-(1-(2-(3,4-dihydroisoquinolin-2(1H)-yl)ethyl)-1H-pyrazol-3-yl)-N-hydroxythiophene-2-carboxamide::CHEMBL385852

SMILES ONC(=O)c1ccc(s1)-c1ccn(CCN2CCc3ccccc3C2)n1

InChI Key InChIKey=XJEMPIZOMZJHDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198212   

TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198212(5-(1-(2-(3,4-dihydroisoquinolin-2(1H)-yl)ethyl)-1H...)
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed