BDBM50198309 (S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester::(S)-ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate::CHEMBL254432::ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE::Monastrol

SMILES CCOC(=O)C1[C@@H](NC(=S)N=C1C)c1cccc(O)c1

InChI Key InChIKey=PSKVISJISBFCKP-KIYNQFGBSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198309   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
University Of Leipzig

LigandPNGBDBM50198309((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...)
Affinity DataIC50:  2.07E+4nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University Of Leipzig

LigandPNGBDBM50198309((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University Of Leipzig

LigandPNGBDBM50198309((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibitory concentration towards kinesin spindle protein activity of ATP hydrolysis in the presence of microtubules measured by ATPase assay...More data for this Ligand-Target Pair