BDBM50198814 CHEMBL390479::N-(7-(2,6-dimethylphenyl)-3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)benzo[e][1,2,4]triazin-5-yl)methanesulfonamide::US8481536, 439::US8481536, 594

SMILES Cc1cccc(C)c1-c1cc(NS(C)(=O)=O)c2nc(Nc3ccc(OCCN4CCCC4)cc3)nnc2c1

InChI Key InChIKey=YEMPBTUCYHTLFL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198814   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198814(CHEMBL390479 | N-(7-(2,6-dimethylphenyl)-3-(4-(2-(...)
Affinity DataIC50:  20.4nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198814(CHEMBL390479 | N-(7-(2,6-dimethylphenyl)-3-(4-(2-(...)
Affinity DataIC50:  21nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198814(CHEMBL390479 | N-(7-(2,6-dimethylphenyl)-3-(4-(2-(...)
Affinity DataIC50:  15.7nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent