BDBM50199522 (+)-huperzine A::(+-)-HA::(-)-1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one(Huperzine A)::(-)-huperazine A::(-)-huperzine A::(-)1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one( (-)-Huperzine A)::(1R,9R)-1-Amino-13-eth-(E)-ylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one::(R)-1-Amino-13-eth-(E)-ylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one::(R)-1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one::(huperazine A)(-)-1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one::1-Amino-13-eth-(E)-ylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one::1-Amino-13-eth-(Z)-ylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one::1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one::1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one((+/-)-Huperzine A)::1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.0*2,7*]trideca-2(7),3,10-trien-5-one((-)-Huperzine A)::1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.0~2,7~]trideca-2(7),3,10-trien-5-one::CHEMBL395280::HUPERAINE A::Hyperazzine A

SMILES: C/C=C/1\[C@@H]2CC3=C([C@]1(CC(=C2)C)N)C=CC(=O)N3

InChI Key: InChIKey=ZRJBHWIHUMBLCN-UHFFFAOYSA-N

Data: 43 IC50  1 Kd

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 50199522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Dog)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72.4	n/a	n/a	n/a	n/a	5.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Pacific electric ray)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50199522 ((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair