BDBM50199611 7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(4-(trifluoromethylthio)phenyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL246953

SMILES CN1CC(c2ccc(SC(F)(F)F)cc2)c2ccc(OCCCN3CCC(F)CC3)cc2C1

InChI Key InChIKey=FYQWSOGFMUPHGU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199611   

TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50199611(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  34nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50199611(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  36nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50199611(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  46nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed