BDBM50199772 3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)butoxy)-2-methylphenyl)propanoic acid::CHEMBL392063

SMILES CCc1ccc(O[C@H](C)CCOc2ccc(CCC(O)=O)c(C)c2)c(c1)-c1ccsc1

InChI Key InChIKey=NAMKLBHSYDFYSO-LJQANCHMSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50199772   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50199772(3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)buto...)
Affinity DataIC50:  568nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-[porpyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50199772(3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)buto...)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl butyric acid from human PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50199772(3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)buto...)
Affinity DataIC50:  5.95E+3nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl butyric acid from human PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50199772(3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)buto...)
Affinity DataIC50:  568nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50199772(3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)buto...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human Gal4-PPARdelta expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50199772(3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)buto...)
Affinity DataIC50:  5.96E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50199772(3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)buto...)
Affinity DataIC50:  8nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50199772(3-(4-((R)-3-(4-ethyl-2-(thiophen-3-yl)phenoxy)buto...)
Affinity DataEC50:  1.67E+3nMAssay Description:Agonist activity at PPARgamma in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed