BDBM50200392 CHEMBL383899::Cyclopropanecarboxylic acid-(3-(4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino)-phenyl)-amide::N-3-4-3-trifluoromethyl)phenylamino)pyrimidin-2-ylamino)phenyl)cyclopropanecarboxamide::N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE
SMILES FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1
InChI Key InChIKey=RDTDWGQDFJPTPD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50200392
Affinity DataIC50: 42nMAssay Description:Inhibition of Aurora-AMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College
Curated by ChEMBL
Weill Cornell Medical College
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of Aurora kinase AChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of Aurora A kinase (unknown origin)More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 386nMAssay Description:Inhibition of BmxChecked by AuthorMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 591nMAssay Description:Inhibition of IGF1RChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 887nMAssay Description:Inhibition of SykChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 131nMAssay Description:Inhibition of LckChecked by AuthorMore data for this Ligand-Target Pair